I found this fascinating, from the Minnesota Supercomputing Institute,,,

What if artificial intelligence could help scientists discover new drugs for healthy aging?

Thomas Hodder, the Life Sciences & Engineering Runner-Up at this year’s Research Computing Exhibition, is developing new ways to identify compounds that may promote healthy aging. Hodder created an AI-powered imaging process that measures heat stress resistance, a trait strongly linked to longevity, in the microscopic worm C. elegans

Traditional lifespan experiments can take weeks and require significant manual effort. Hodder’s approach automates much of the process, allowing researchers to rapidly screen thousands of compounds and identify promising candidates more efficiently. Using this method, his team discovered 14 previously unknown drugs that extend worm lifespan.

One of the biggest challenges was developing and validating the assay itself. Hodder spent nearly two years refining the method before it was ready to detect potential drug candidates. Throughout that process, he relied on high-performance computing resources from the Minnesota Supercomputing Institute to process large imaging datasets, test software, and store research data.